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Slowed Intestine Movement. Paralytic ileus is actually a style of ileus where your intestines are not able to transfer food items as a result of them. Methadone could make this affliction even worse.​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​â